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53 days to first decision for reviewed manuscripts only
48 days to first decision for all manuscripts
182 days from submission to acceptance
23 days from acceptance to publication
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We conducted a correlative study for E2399, a function preservation trial for resectable locally advanced oropharynx and larynx cancer, to prospectively assess effects of chemoradiation (CCR) on quality of lif...
Citation: Cancers of the Head & Neck 2020 5:12
Human papillomavirus (HPV) associated head and neck squamous cell carcinoma (HNSCC) has a better prognosis than HNSCC due to other risk factors. However, there is significant heterogeneity within HPV-associate...
Citation: Cancers of the Head & Neck 2020 5:11
Cancer burden in sub-Saharan Africa is on the rise with one-third of cancers estimated to be caused by infectious agents. Head and neck squamous cell cancer (HNSCC) is the sixth most common malignancy in sub-S...
Citation: Cancers of the Head & Neck 2020 5:10
Comprehensive molecular characterization of head and neck squamous cell carcinoma (HNSCC) has led to the identification of distinct molecular subgroups with fundamental differences in biological properties and...
Citation: Cancers of the Head & Neck 2020 5:9
The latency of the swallowing reflex is an important factor causing dysphagia in head and neck cancer patients. Although there are many reports comparing voluntary swallowing function before and after treatmen...
Citation: Cancers of the Head & Neck 2020 5:8
Citation: Cancers of the Head & Neck 2020 5:7
Recent advancements in computational power, machine learning, and artificial intelligence technology have enabled automated evaluation of medical images to generate quantitative diagnostic and prognostic bioma...
Citation: Cancers of the Head & Neck 2020 5:6
Angiogenesis is an integral aspect of the growth and proliferation of solid tumors, including head and neck squamous cell carcinoma (HNSCC), and has potential implications in prognosis and treatment of both lo...
Citation: Cancers of the Head & Neck 2020 5:5
There remains up to a 50% recurrence rate in advanced p16- head and neck squamous cell carcinoma with current standard of care treatment. In an attempt to improve survival, multiple trials administering induct...
Citation: Cancers of the Head & Neck 2020 5:4
As the number of indicated malignancies for which immune checkpoint inhibitor therapy such as pembrolizumab grows the descriptions of associated immune-related adverse events (irAEs) increases as well. On rare...
Citation: Cancers of the Head & Neck 2020 5:3
For many years, head and neck squamous cell carcinoma (HNSCC) has been considered as a single entity. However, in the last decades HNSCC complexity and heterogeneity have been recognized. In parallel, high-thr...
Citation: Cancers of the Head & Neck 2020 5:2
Although there have been dramatic improvements in radiotherapy for head and neck squamous cell carcinoma (HNSCC), including robust intensity modulation and daily image guidance, these advances are not able to ...
Citation: Cancers of the Head & Neck 2020 5:1
The genomic landscape of head and neck cancer has been reported through The Cancer Genome Atlas project. We attempt to determine if high-risk human papillomavirus (HPV) or frequently mutated genes are correlat...
Citation: Cancers of the Head & Neck 2019 4:5
The optimal treatment for regional lymphatic recurrences from head and neck cancer has not been fully established. In order to explore the therapeutic benefit of surgical resection and adjuvant brachytherapy, ...
Citation: Cancers of the Head & Neck 2019 4:4
Compared to HPV-negative head and neck squamous cell carcinomas (HNSCCs), HPV-positive HNSCCs are associated with a favorable prognosis in part due to their improved treatment sensitivity. Inactivating mutatio...
Citation: Cancers of the Head & Neck 2019 4:3
Patients with head and neck cancer (HNC) experience significant physical and psychological distress, which have a negative impact on their quality of life (QOL). Few strategies have been studied to help improv...
Citation: Cancers of the Head & Neck 2019 4:2
Human papillomavirus-associated oropharyngeal cancer (HPV-OSCC) is rapidly increasing in incidence and has unique epidemiologic, molecular, and biologic characteristics. Standard combined modality therapies fo...
Citation: Cancers of the Head & Neck 2019 4:1
Understanding of oropharyngeal squamous cell carcinoma has significantly progressed over the last decades, and the concept that this disease can be subdivided into two distinct entities based on human papillom...
Citation: Cancers of the Head & Neck 2018 3:12
Increased treatment package time is an independent poor prognostic factor for outcomes in head and neck squamous cell carcinoma (HNSCC). Similarly the timeliness of treatment initiation is a risk factor for di...
Citation: Cancers of the Head & Neck 2018 3:11
Information on patients with differentiated thyroid carcinoma in South Africa is limited. The objective of this study was to review demographics and tumour characteristics in a cohort of patients with differen...
Citation: Cancers of the Head & Neck 2018 3:10
Despite improvements in diagnosis and patient management, survival and prognostic factors of patients with oral squamous cell carcinoma (OSCC) remains largely unknown in most of Sub Saharan Africa.
Citation: Cancers of the Head & Neck 2018 3:9
HPV related OPSCC has a distinct behavior and improved outcome. As immunotherapy has recently evolved into a new standard for advanced (SCCHN), trials for high-risk SCCHN have trended to encompass both HPV rel...
Citation: Cancers of the Head & Neck 2018 3:8
Airline crew are exposed to ionizing radiation as part of their occupation and have a documented increased risk of melanoma and cataracts. However, whether their occupation predisposes them to an increased ris...
Citation: Cancers of the Head & Neck 2018 3:7
Significant weight loss and malnutrition are common in patients with head and neck cancer, despite advances in treatment and development of evidenced-based guidelines. The aim of this study was to assess adher...
Citation: Cancers of the Head & Neck 2018 3:6
Extracapsular extension (ECE) is a well-established prognostic feature in squamous cell cancers of the head and neck. Although some extrapolate data from mucosal head and neck cancer to include ECE as a high-r...
Citation: Cancers of the Head & Neck 2018 3:5
Human papilloma virus (HPV)-associated head and neck cancer is now recognized as a distinct clinical entity from HPV-negative tumors, which are primarily associated with tobacco and alcohol exposure.Little is...
Citation: Cancers of the Head & Neck 2018 3:4
The landscape of head and neck squamous cell carcinoma (HNSCC) has been changing rapidly due to growing proportion of HPV-related disease and development of new therapeutic agents. At the same time, there has ...
Citation: Cancers of the Head & Neck 2018 3:3
Circulating interleukin-6 (IL-6) improves outcome prediction for second primary cancer (SPC) in head and neck cancer (HNC) patients. This study aimed to identify factors associated with IL-6 serum levels in HN...
Citation: Cancers of the Head & Neck 2018 3:1
Synchronous squamous cell carcinoma of the head and neck (HNSCC) and non-Hodgkin’s lymphoma is a rare clinical scenario. It is unknown whether the R-CHOP chemotherapy for lymphoma would also be active against ...
Citation: Cancers of the Head & Neck 2018 3:2
The present study evaluated clinical outcomes for patients with head and neck squamous cell carcinoma presenting with N3 nodal disease.
Citation: Cancers of the Head & Neck 2017 2:8
The development of orally active, multitargeted kinase inhibitors (MKIs) represents a significant advance in the treatment of progressive, metastatic thyroid cancer. Lenvatinib, an MKI targeting vascular endot...
Citation: Cancers of the Head & Neck 2017 2:7
Treatment modalities of head and neck squamous cell cancer include surgery, radiation, chemotherapy, targeted agents and immune checkpoint inhibition. Treatment is often toxic and can affect long-term function...
Citation: Cancers of the Head & Neck 2017 2:6
Transoral endoscopic head and neck surgery (eHNS), including transoral laser microsurgery (TLM) and transoral robotic surgery (TORS), provides access to subsites in the head and neck that have traditionally be...
Citation: Cancers of the Head & Neck 2017 2:5
To find out how chemotherapy given prior to concurrent chemoradiotherapy compares with concurrent chemoradiation alone in the treatment of locally advanced nasopharyngeal cancer.
Citation: Cancers of the Head & Neck 2017 2:4
Small cell carcinoma (SCC) is a rare variant of head and neck cancer characterized by a high-grade neuroendocrine cancer with similar features to small cell lung carcinoma (SCLC). Human papillomavirus (HPV) is...
Citation: Cancers of the Head & Neck 2017 2:3
Locally advanced (stage III or IV) squamous cell carcinoma of the head and neck (SCCHN) often requires multimodal treatment, consisting of a combination of surgery, radiation, and/or systemic therapy, namely c...
Citation: Cancers of the Head & Neck 2017 2:2
Thyroid cancer incidence is rapidly increasing due to increased detection and diagnosis of indolent thyroid cancer, i.e. cancer that is likely to be clinically insignificant. Clinical, radiologic, and patholog...
Citation: Cancers of the Head & Neck 2017 2:1
Current adjuvant treatment guidelines for oropharyngeal squamous cell carcinoma treated with primary surgery are based on studies that predate the human papillomavirus (HPV) era. HPV-associated oropharynx carc...
Citation: Cancers of the Head & Neck 2016 1:18
Oropharyngeal cancer is frequently associated with human papilloma virus, that also represents a strong prognostic factor. Local relaps and treatment-related complications are frequent, whereas distant metasta...
Citation: Cancers of the Head & Neck 2016 1:16
For complex reconstruction of osseous defects of the head and neck, three-dimensional (3D) computer planning has been available for over 20 years. However, despite its availability and recent refinements, it i...
Citation: Cancers of the Head & Neck 2016 1:17
The objective of this article is to review and summarize the extant literature on head and neck cancer (HNC) patients’ informational needs and to characterize emerging issues in this patient population in orde...
Citation: Cancers of the Head & Neck 2016 1:15
Venous thromboembolism (VTE) is a major cause of perioperative morbidity and mortality. Historically, otolaryngology surgery has been seen as very low risk of VTE, given the relatively short procedures and hea...
Citation: Cancers of the Head & Neck 2016 1:13
Therapeutic improvements and epidemiologic changes in head and neck cancer (HNC) over the last three decades have led to increased numbers of survivors, resulting in greater need for continuing management of o...
Citation: Cancers of the Head & Neck 2016 1:14
Head and neck squamous cell carcinoma (HNSCC) represents a model of escape from anti-tumor immunity. The high frequency of p53 tumor suppressor loss in HNSCC leads to genomic instability and immune stimulation...
Citation: Cancers of the Head & Neck 2016 1:12
Germline CYLD mutation is associated with the development of a rare inheritable syndrome, called the CYLD cutaneous syndrome. Patients with this syndrome are distinctly presented with multiple tumors in the head ...
Citation: Cancers of the Head & Neck 2016 1:10
Salivary gland carcinomas are notoriously resistant to therapy and no standard of care exists. Due to the rarity of these malignancies, various histologies, and wide ranging clinical behavior it has been diffi...
Citation: Cancers of the Head & Neck 2016 1:11
Concurrent chemotherapy and radiation (CTRT) improves disease-free survival in locally advanced head and neck cancer but is associated with numerous acute and chronic toxicities resulting in substantial altera...
Citation: Cancers of the Head & Neck 2016 1:9
Treatment of locally advanced squamous cell carcinomas of the head and neck (SCCHN) remains unsatisfactory. Although the addition of concurrent radiochemotherapy (RCT) or the combination of radiotherapy with b...
Citation: Cancers of the Head & Neck 2016 1:8
Given the marked difference in clinical presentation and treatment response based on human papilloma virus (HPV) status, HPV-associated oropharyngeal squamous cell carcinoma is now viewed as a distinct biologi...
Citation: Cancers of the Head & Neck 2016 1:6
The purpose of this study was to identify preoperative patient characteristics associated with the incidence of positive surgical margins or lymph node extracapsular extension (ECE), which necessitate adjuvant...
Citation: Cancers of the Head & Neck 2016 1:7
Speed
53 days to first decision for reviewed manuscripts only
48 days to first decision for all manuscripts
182 days from submission to acceptance
23 days from acceptance to publication
Usage
45,778 Downloads
8 Altmetric Mentions