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  1. Content type: Research

    Extracapsular extension (ECE) is a well-established prognostic feature in squamous cell cancers of the head and neck. Although some extrapolate data from mucosal head and neck cancer to include ECE as a high-r...

    Authors: Shayan Cheraghlou, Phoebe K. Yu, Michael D. Otremba, Saral Mehra, Wendell G. Yarbrough and Benjamin L. Judson

    Citation: Cancers of the Head & Neck 2018 3:5

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  2. Content type: Research

    Human papilloma virus (HPV)-associated head and neck cancer is now recognized as a distinct clinical entity from HPV-negative tumors, which are primarily associated with tobacco and alcohol exposure.Little is...

    Authors: Hong Li, Henry S. Park, Heather A. Osborn and Benjamin L. Judson

    Citation: Cancers of the Head & Neck 2018 3:4

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  3. Content type: Research

    Circulating interleukin-6 (IL-6) improves outcome prediction for second primary cancer (SPC) in head and neck cancer (HNC) patients. This study aimed to identify factors associated with IL-6 serum levels in HN...

    Authors: Sylvine Carrondo Cottin, Stéphane Turcotte, Pierre Douville, François Meyer and Isabelle Bairati

    Citation: Cancers of the Head & Neck 2018 3:1

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  4. Content type: Case report

    Synchronous squamous cell carcinoma of the head and neck (HNSCC) and non-Hodgkin’s lymphoma is a rare clinical scenario. It is unknown whether the R-CHOP chemotherapy for lymphoma would also be active against ...

    Authors: Ting Martin Ma, Hyunseok Kang, Steven P. Rowe and Ana P. Kiess

    Citation: Cancers of the Head & Neck 2018 3:2

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  5. Content type: Research

    The present study evaluated clinical outcomes for patients with head and neck squamous cell carcinoma presenting with N3 nodal disease.

    Authors: Matthew E. Witek, Aaron M. Wieland, Shuai Chen, Tabassum A. Kennedy, Craig R. Hullett, Evan Liang, Gregory K. Hartig, Randy J. Kimple and Paul M. Harari

    Citation: Cancers of the Head & Neck 2017 2:8

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  6. Content type: Review

    Treatment modalities of head and neck squamous cell cancer include surgery, radiation, chemotherapy, targeted agents and immune checkpoint inhibition. Treatment is often toxic and can affect long-term function...

    Authors: Nnamdi Eze, Ying-Chun Lo and Barbara Burtness

    Citation: Cancers of the Head & Neck 2017 2:6

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  7. Content type: Research

    Transoral endoscopic head and neck surgery (eHNS), including transoral laser microsurgery (TLM) and transoral robotic surgery (TORS), provides access to subsites in the head and neck that have traditionally be...

    Authors: David W. Schoppy, Michael E. Kupferman, Amy C. Hessel, Diana M. Bell, Elizabeth M. Garland, Edward J. Damrose and F. Christopher Holsinger

    Citation: Cancers of the Head & Neck 2017 2:5

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  8. Content type: Research

    To find out how chemotherapy given prior to concurrent chemoradiotherapy compares with concurrent chemoradiation alone in the treatment of locally advanced nasopharyngeal cancer.

    Authors: Joel Yarney, Naa A. Aryeetey, Alice Mensah, Emmanuel D. Kitcher, Verna Vanderpuye, Charles Aidoo and Kenneth Baidoo

    Citation: Cancers of the Head & Neck 2017 2:4

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  9. Content type: Case report

    Small cell carcinoma (SCC) is a rare variant of head and neck cancer characterized by a high-grade neuroendocrine cancer with similar features to small cell lung carcinoma (SCLC). Human papillomavirus (HPV) is...

    Authors: Marcelo Bonomi, Tamjeed Ahmed, David Warner, Joshua Waltonen, Christopher Sullivan, Mercedes Porosnicu, Katharine Batt, Jimmy Ruiz and James Cappellari

    Citation: Cancers of the Head & Neck 2017 2:3

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  10. Content type: Review

    Locally advanced (stage III or IV) squamous cell carcinoma of the head and neck (SCCHN) often requires multimodal treatment, consisting of a combination of surgery, radiation, and/or systemic therapy, namely c...

    Authors: Paolo Bossi and Francesca Platini

    Citation: Cancers of the Head & Neck 2017 2:2

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  11. Content type: Review

    Thyroid cancer incidence is rapidly increasing due to increased detection and diagnosis of indolent thyroid cancer, i.e. cancer that is likely to be clinically insignificant. Clinical, radiologic, and patholog...

    Authors: Lewis D. Hahn, Christian A. Kunder, Michelle M. Chen, Lisa A. Orloff and Terry S. Desser

    Citation: Cancers of the Head & Neck 2017 2:1

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  12. Content type: Case report

    Oropharyngeal cancer is frequently associated with human papilloma virus, that also represents a strong prognostic factor. Local relaps and treatment-related complications are frequent, whereas distant metasta...

    Authors: Daris Ferrari, Carla Codecà, Giulia Viale, Barbara Bocci, Francesca Broggio, Francesca Crepaldi, Martina Violati, Andrea Luciani, Dario Bauer, Laura Moneghini, Gaetano Bulfamante and Paolo Foa

    Citation: Cancers of the Head & Neck 2016 1:16

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  13. Content type: Review

    For complex reconstruction of osseous defects of the head and neck, three-dimensional (3D) computer planning has been available for over 20 years. However, despite its availability and recent refinements, it i...

    Authors: Diana N. Kirke, Randall P. Owen, Vincent Carrao, Brett A Miles and Jason I. Kass

    Citation: Cancers of the Head & Neck 2016 1:17

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  14. Content type: Review

    Venous thromboembolism (VTE) is a major cause of perioperative morbidity and mortality. Historically, otolaryngology surgery has been seen as very low risk of VTE, given the relatively short procedures and hea...

    Authors: Faisal I. Ahmad and Daniel R. Clayburgh

    Citation: Cancers of the Head & Neck 2016 1:13

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  15. Content type: Review

    Therapeutic improvements and epidemiologic changes in head and neck cancer (HNC) over the last three decades have led to increased numbers of survivors, resulting in greater need for continuing management of o...

    Authors: Firoozeh Samim, Joel B. Epstein, Zachary S. Zumsteg, Allen S. Ho and Andrei Barasch

    Citation: Cancers of the Head & Neck 2016 1:14

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  16. Content type: Review

    Head and neck squamous cell carcinoma (HNSCC) represents a model of escape from anti-tumor immunity. The high frequency of p53 tumor suppressor loss in HNSCC leads to genomic instability and immune stimulation...

    Authors: Ruth J. Davis, Robert L. Ferris and Nicole C. Schmitt

    Citation: Cancers of the Head & Neck 2016 1:12

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  17. Content type: Review

    Germline CYLD mutation is associated with the development of a rare inheritable syndrome, called the CYLD cutaneous syndrome. Patients with this syndrome are distinctly presented with multiple tumors in the head ...

    Authors: Krista Roberta Verhoeft, Hoi Lam Ngan and Vivian Wai Yan Lui

    Citation: Cancers of the Head & Neck 2016 1:10

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  18. Content type: Review

    Treatment of locally advanced squamous cell carcinomas of the head and neck (SCCHN) remains unsatisfactory. Although the addition of concurrent radiochemotherapy (RCT) or the combination of radiotherapy with b...

    Authors: Ingeborg Tinhofer, Volker Budach, Korinna Jöhrens and Ulrich Keilholz

    Citation: Cancers of the Head & Neck 2016 1:8

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