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  1. Review

    Biomarker driven treatment of head and neck squamous cell cancer

    Treatment modalities of head and neck squamous cell cancer include surgery, radiation, chemotherapy, targeted agents and immune checkpoint inhibition. Treatment is often toxic and can affect long-term function...

    Nnamdi Eze, Ying-Chun Lo and Barbara Burtness

    Cancers of the Head & Neck 2017 2:6

    Published on: 29 August 2017

  2. Research

    Transoral endoscopic head and neck surgery (eHNS) for minor salivary gland tumors of the oropharynx

    Transoral endoscopic head and neck surgery (eHNS), including transoral laser microsurgery (TLM) and transoral robotic surgery (TORS), provides access to subsites in the head and neck that have traditionally be...

    David W. Schoppy, Michael E. Kupferman, Amy C. Hessel, Diana M. Bell, Elizabeth M. Garland, Edward J. Damrose and F. Christopher Holsinger

    Cancers of the Head & Neck 2017 2:5

    Published on: 31 May 2017

  3. Research

    Does concurrent chemoradiotherapy preceded by chemotherapy improve survival in locally advanced nasopharyngeal cancer patients? Experience from Ghana

    To find out how chemotherapy given prior to concurrent chemoradiotherapy compares with concurrent chemoradiation alone in the treatment of locally advanced nasopharyngeal cancer.

    Joel Yarney, Naa A. Aryeetey, Alice Mensah, Emmanuel D. Kitcher, Verna Vanderpuye, Charles Aidoo and Kenneth Baidoo

    Cancers of the Head & Neck 2017 2:4

    Published on: 20 April 2017

  4. Case report

    Human papillomavirus-related small cell carcinoma of the oropharynx: a case report and literature review

    Small cell carcinoma (SCC) is a rare variant of head and neck cancer characterized by a high-grade neuroendocrine cancer with similar features to small cell lung carcinoma (SCLC). Human papillomavirus (HPV) is...

    Marcelo Bonomi, Tamjeed Ahmed, David Warner, Joshua Waltonen, Christopher Sullivan, Mercedes Porosnicu, Katharine Batt, Jimmy Ruiz and James Cappellari

    Cancers of the Head & Neck 2017 2:3

    Published on: 6 February 2017

  5. Review

    Radiotherapy plus EGFR inhibitors: synergistic modalities

    Locally advanced (stage III or IV) squamous cell carcinoma of the head and neck (SCCHN) often requires multimodal treatment, consisting of a combination of surgery, radiation, and/or systemic therapy, namely c...

    Paolo Bossi and Francesca Platini

    Cancers of the Head & Neck 2017 2:2

    Published on: 18 January 2017

  6. Review

    Indolent thyroid cancer: knowns and unknowns

    Thyroid cancer incidence is rapidly increasing due to increased detection and diagnosis of indolent thyroid cancer, i.e. cancer that is likely to be clinically insignificant. Clinical, radiologic, and patholog...

    Lewis D. Hahn, Christian A. Kunder, Michelle M. Chen, Lisa A. Orloff and Terry S. Desser

    Cancers of the Head & Neck 2017 2:1

    Published on: 11 January 2017

  7. Case report

    An unusual case of tracheo-pleural fistula and cardiac metastases in oropharyngeal carcinoma: a case report and review of the literature

    Oropharyngeal cancer is frequently associated with human papilloma virus, that also represents a strong prognostic factor. Local relaps and treatment-related complications are frequent, whereas distant metasta...

    Daris Ferrari, Carla Codecà, Giulia Viale, Barbara Bocci, Francesca Broggio, Francesca Crepaldi, Martina Violati, Andrea Luciani, Dario Bauer, Laura Moneghini, Gaetano Bulfamante and Paolo Foa

    Cancers of the Head & Neck 2016 1:16

    Published on: 15 December 2016

  8. Review

    Using 3D computer planning for complex reconstruction of mandibular defects

    For complex reconstruction of osseous defects of the head and neck, three-dimensional (3D) computer planning has been available for over 20 years. However, despite its availability and recent refinements, it i...

    Diana N. Kirke, Randall P. Owen, Vincent Carrao, Brett A Miles and Jason I. Kass

    Cancers of the Head & Neck 2016 1:17

    Published on: 9 December 2016

  9. Review

    Venous thromboembolism in head and neck cancer surgery

    Venous thromboembolism (VTE) is a major cause of perioperative morbidity and mortality. Historically, otolaryngology surgery has been seen as very low risk of VTE, given the relatively short procedures and hea...

    Faisal I. Ahmad and Daniel R. Clayburgh

    Cancers of the Head & Neck 2016 1:13

    Published on: 1 November 2016

  10. Review

    Oral and dental health in head and neck cancer survivors

    Therapeutic improvements and epidemiologic changes in head and neck cancer (HNC) over the last three decades have led to increased numbers of survivors, resulting in greater need for continuing management of o...

    Firoozeh Samim, Joel B. Epstein, Zachary S. Zumsteg, Allen S. Ho and Andrei Barasch

    Cancers of the Head & Neck 2016 1:14

    Published on: 19 October 2016

  11. Review

    The cylindromatosis (CYLD) gene and head and neck tumorigenesis

    Germline CYLD mutation is associated with the development of a rare inheritable syndrome, called the CYLD cutaneous syndrome. Patients with this syndrome are distinctly presented with multiple tumors in the head ...

    Krista Roberta Verhoeft, Hoi Lam Ngan and Vivian Wai Yan Lui

    Cancers of the Head & Neck 2016 1:10

    Published on: 8 September 2016

  12. Review

    Systemic therapy for recurrent or metastatic salivary gland malignancies

    Salivary gland carcinomas are notoriously resistant to therapy and no standard of care exists. Due to the rarity of these malignancies, various histologies, and wide ranging clinical behavior it has been diffi...

    Ashish V. Chintakuntlawar, Scott H. Okuno and Katharine A. Price

    Cancers of the Head & Neck 2016 1:11

    Published on: 1 September 2016

  13. Research

    Pretreatment predictors of adjuvant chemoradiation in patients receiving transoral robotic surgery for squamous cell carcinoma of the oropharynx: a case control study

    The purpose of this study was to identify preoperative patient characteristics associated with the incidence of positive surgical margins or lymph node extracapsular extension (ECE), which necessitate adjuvant...

    Harry E. Subramanian, Henry S. Park, Andrea Barbieri, Amit Mahajan, Benjamin L. Judson, Saral Mehra, Wendell G. Yarbrough, Barbara A. Burtness and Zain A. Husain

    Cancers of the Head & Neck 2016 1:7

    Published on: 4 July 2016

  14. Review

    Genomically personalized therapy in head and neck cancer

    The current treatment paradigm in head and neck cancer does not adequately address its clinical and biological heterogeneity. Data from genomic profiling studies in head and neck squamous cell carcinoma (HNSCC...

    Kyaw L. Aung and Lillian L. Siu

    Cancers of the Head & Neck 2016 1:2

    Published on: 9 June 2016

  15. Review

    Genomic insights into head and neck cancer

    Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and is frequently impervious to curative treatment efforts. Similar to other cancers associated with prolonged exposure t...

    Tim N. Beck and Erica A. Golemis

    Cancers of the Head & Neck 2016 1:1

    Published on: 3 June 2016

  16. Research

    Employment and return to work following chemoradiation in patient with HPV-related oropharyngeal cancer

    Human papillomavirus (HPV)-positive oropharyngeal cancer primarily affects working-age adults. Chemotherapy and radiation (CTRT) used to treat this disease may adversely impact a survivors’ ability to work aft...

    Shrujal S. Baxi, Talya Salz, Han Xiao, Coral L. Atoria, Alan Ho, Stephanie Smith-Marrone, Eric J. Sherman, Nancy Y. Lee, Elena B. Elkin and David G. Pfister

    Cancers of the Head & Neck 2016 1:4

    Published on: 3 June 2016

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