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Research
Transoral endoscopic head and neck surgery (eHNS), including transoral laser microsurgery (TLM) and transoral robotic surgery (TORS), provides access to subsites in the head and neck that have traditionally be...
Cancers of the Head & Neck 2017 2:5
Published on: 31 May 2017
Research
To find out how chemotherapy given prior to concurrent chemoradiotherapy compares with concurrent chemoradiation alone in the treatment of locally advanced nasopharyngeal cancer.
Cancers of the Head & Neck 2017 2:4
Published on: 20 April 2017
Case report
Small cell carcinoma (SCC) is a rare variant of head and neck cancer characterized by a high-grade neuroendocrine cancer with similar features to small cell lung carcinoma (SCLC). Human papillomavirus (HPV) is...
Cancers of the Head & Neck 2017 2:3
Published on: 6 February 2017
Review
Locally advanced (stage III or IV) squamous cell carcinoma of the head and neck (SCCHN) often requires multimodal treatment, consisting of a combination of surgery, radiation, and/or systemic therapy, namely c...
Cancers of the Head & Neck 2017 2:2
Published on: 18 January 2017
Review
Thyroid cancer incidence is rapidly increasing due to increased detection and diagnosis of indolent thyroid cancer, i.e. cancer that is likely to be clinically insignificant. Clinical, radiologic, and patholog...
Cancers of the Head & Neck 2017 2:1
Published on: 11 January 2017
Review
Current adjuvant treatment guidelines for oropharyngeal squamous cell carcinoma treated with primary surgery are based on studies that predate the human papillomavirus (HPV) era. HPV-associated oropharynx carc...
Cancers of the Head & Neck 2016 1:18
Published on: 20 December 2016
Case report
Oropharyngeal cancer is frequently associated with human papilloma virus, that also represents a strong prognostic factor. Local relaps and treatment-related complications are frequent, whereas distant metasta...
Cancers of the Head & Neck 2016 1:16
Published on: 15 December 2016
Review
For complex reconstruction of osseous defects of the head and neck, three-dimensional (3D) computer planning has been available for over 20 years. However, despite its availability and recent refinements, it i...
Cancers of the Head & Neck 2016 1:17
Published on: 9 December 2016
Review
The objective of this article is to review and summarize the extant literature on head and neck cancer (HNC) patients’ informational needs and to characterize emerging issues in this patient population in orde...
Cancers of the Head & Neck 2016 1:15
Published on: 11 November 2016
Review
Venous thromboembolism (VTE) is a major cause of perioperative morbidity and mortality. Historically, otolaryngology surgery has been seen as very low risk of VTE, given the relatively short procedures and hea...
Cancers of the Head & Neck 2016 1:13
Published on: 1 November 2016
Review
Therapeutic improvements and epidemiologic changes in head and neck cancer (HNC) over the last three decades have led to increased numbers of survivors, resulting in greater need for continuing management of o...
Cancers of the Head & Neck 2016 1:14
Published on: 19 October 2016
Review
Head and neck squamous cell carcinoma (HNSCC) represents a model of escape from anti-tumor immunity. The high frequency of p53 tumor suppressor loss in HNSCC leads to genomic instability and immune stimulation...
Cancers of the Head & Neck 2016 1:12
Published on: 1 October 2016
Review
Germline CYLD mutation is associated with the development of a rare inheritable syndrome, called the CYLD cutaneous syndrome. Patients with this syndrome are distinctly presented with multiple tumors in the head ...
Cancers of the Head & Neck 2016 1:10
Published on: 8 September 2016
Review
Salivary gland carcinomas are notoriously resistant to therapy and no standard of care exists. Due to the rarity of these malignancies, various histologies, and wide ranging clinical behavior it has been diffi...
Cancers of the Head & Neck 2016 1:11
Published on: 1 September 2016
Review
Concurrent chemotherapy and radiation (CTRT) improves disease-free survival in locally advanced head and neck cancer but is associated with numerous acute and chronic toxicities resulting in substantial altera...
Cancers of the Head & Neck 2016 1:9
Published on: 17 August 2016
Review
Treatment of locally advanced squamous cell carcinomas of the head and neck (SCCHN) remains unsatisfactory. Although the addition of concurrent radiochemotherapy (RCT) or the combination of radiotherapy with b...
Cancers of the Head & Neck 2016 1:8
Published on: 10 August 2016
Review
Given the marked difference in clinical presentation and treatment response based on human papilloma virus (HPV) status, HPV-associated oropharyngeal squamous cell carcinoma is now viewed as a distinct biologi...
Cancers of the Head & Neck 2016 1:6
Published on: 11 July 2016
Research
The purpose of this study was to identify preoperative patient characteristics associated with the incidence of positive surgical margins or lymph node extracapsular extension (ECE), which necessitate adjuvant...
Cancers of the Head & Neck 2016 1:7
Published on: 4 July 2016
Review
Though treatments for head and neck cancer have improved in recent years, significant variation persists in the delivery of surgery, radiation therapy, and systemic therapy to patients throughout the United St...
Cancers of the Head & Neck 2016 1:5
Published on: 13 June 2016
Review
The current treatment paradigm in head and neck cancer does not adequately address its clinical and biological heterogeneity. Data from genomic profiling studies in head and neck squamous cell carcinoma (HNSCC...
Cancers of the Head & Neck 2016 1:2
Published on: 9 June 2016
Review
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and is frequently impervious to curative treatment efforts. Similar to other cancers associated with prolonged exposure t...
Cancers of the Head & Neck 2016 1:1
Published on: 3 June 2016
Research
Human papillomavirus (HPV)-positive oropharyngeal cancer primarily affects working-age adults. Chemotherapy and radiation (CTRT) used to treat this disease may adversely impact a survivors’ ability to work aft...
Cancers of the Head & Neck 2016 1:4
Published on: 3 June 2016
Editorial
Cancers of the Head & Neck 2016 1:3
Published on: 3 June 2016
