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Table 2 Clinical characteristics of TCGA HPV(+) cohort by NSD1 mutation status

From: NSD1 mutations by HPV status in head and neck cancer: differences in survival and response to DNA-damaging agents

  Mutant NSD1, n = 6 Wild-type NSD1, n = 59 p-value*
n % n %  
Avg. age at diagnosis (years) 51.8   57.8   0.15
Sex      0.41
 Female 0 0.0 6 10.2  
 Male 6 100.0 53 89.8  
Race      0.57
 Black or African American 0 0.0 3 5.1  
 White 6 100.0 56 94.9  
Smoking History Category      0.53
 Never Smoker 3 50.0 18 30.5  
 Current Smoker 0 0.0 14 23.7  
 Former Smoker 3 50.0 26 44.1  
 Unknown 0 0.0 1 1.7  
Alcohol Use      0.90
 No 1 16.7 13 22.0  
 Yes 5 83.3 45 76.3  
 Unknown 0 0.0 1 1.7  
Stagea      0.65
 Stage I, II 1 16.7 11 18.6  
 Stage III 0 0.0 7 11.9  
 Stage IV 5 83.3 41 69.5  
  1. *p-value is calculated from chi-square test for categorical variables or Wilcoxon rank-sum test for age (continuous)
  2. aStages assigned using AJCC 7th edition (63%), 6th edition (37%)