Fig. 6

Cells with NSD1 mutations show increased sensitivity to cisplatin, but not to other DNA-damaging agents. Pan-cancer cohort showing sensitivity of cells with or without NSD1 mutations to treatment with (a) cisplatin (18 mutant and 798 wild-type cell lines); (b) bleomycin (18 mutant and 817 wild-type cell lines); (c) etoposide (18 mutant and 834 wild-type cell lines); and (d) paclitaxel (8 mutant and 377 wild-type cell lines). Adapted from the Wellcome Sanger Institute website Cancerrxgene.org