Nodal disease predicts recurrence whereas other traditional factors affect survival in a cohort of South African patients with differentiated thyroid carcinoma

Table 2 Univariate analyses for RFS

Variable	N (204)	10-year RFS %	p-value (log rank)	Prognostically unfavourable subgroup
Pathology
Follicular and Hurthle	74	81	ns	–
Papillary	129	77
Gender
Male	34	78	0.04	Male
Female	170	81
Age
< 45	109	78	ns
≥ 45	95	79
T stage
T0	1	100
T1	49	85	0.038^Ϯ
T2	76	85	0.011*	T4
T3	48	75
T4^Ϯ*	16	60
TX	14	63
Extra-thyroid extension
No	171	87	0.02*	Extra-thyroid
Yes*	23	64		extension
Unknown	10	53
Nodal status
N0^Ϯ*	130	93		N1
N1	63	76	0.004*	and
NX (unknown)	11	30	< 0.001^Ϯ	unknown
Residual tumour
R0/1^Ϯ	175	88
R2^Ϯ	15	100		Unknown
Unknown	14	24	< 0.001^Ϯ
Post-operative risk stratification for risk of recurrence
High	17	72	0.05*	High, intermediate
Intermediate^Ϯ	98	74	0.02*	and
Low*	82	90		unknown
Unknown	7	24	0.006^Ϯ; 0.001*

Symbols denote the associated prognostic variable for each p-value. Patients who presented with unresectable primary tumours and distant metastases were excluded (n = 27). These patients were not treated with curative intent and therefore could not be included in the recurrence free survival analysis

ISSN: 2059-7347