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Table 2 Univariate analyses for RFS

From: Nodal disease predicts recurrence whereas other traditional factors affect survival in a cohort of South African patients with differentiated thyroid carcinoma

Variable N (204) 10-year RFS % p-value (log rank) Prognostically unfavourable subgroup
Pathology
 Follicular and Hurthle 74 81 ns
 Papillary 129 77   
Gender
 Male 34 78 0.04 Male
 Female 170 81   
Age
 <  45 109 78 ns  
 ≥ 45 95 79   
T stage
 T0 1 100   
 T1 49 85 0.038Ϯ  
 T2 76 85 0.011* T4
 T3 48 75   
 T4Ϯ* 16 60   
 TX 14 63   
Extra-thyroid extension
 No 171 87 0.02* Extra-thyroid
 Yes* 23 64   extension
 Unknown 10 53   
Nodal status
 N0Ϯ* 130 93   N1
 N1 63 76 0.004* and
 NX (unknown) 11 30 <  0.001Ϯ unknown
Residual tumour
 R0/1Ϯ 175 88   
 R2Ϯ 15 100   Unknown
 Unknown 14 24 <  0.001Ϯ  
Post-operative risk stratification for risk of recurrence
 High 17 72 0.05* High, intermediate
 IntermediateϮ 98 74 0.02* and
 Low* 82 90   unknown
 Unknown 7 24 0.006Ϯ; 0.001*  
  1. Symbols denote the associated prognostic variable for each p-value. Patients who presented with unresectable primary tumours and distant metastases were excluded (n = 27). These patients were not treated with curative intent and therefore could not be included in the recurrence free survival analysis