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Table 1 The main omics techniques and their characteristics: the biological material analyzed, the major methodologies applied and the type of information achievable with them

From: Transcriptomics and Epigenomics in head and neck cancer: available repositories and molecular signatures

Omics nameMaterial analyzedMethodologiesType of information
GenomicsDNAWhole-genome sequencingComplete genome sequence for identification of coding and non-coding sequence variants
Exome sequencing or clinical exome-sequencingSequencing of protein-coding regions of the genome or genes known to be associated to a clinical phenotype
Comparative genomic hybridization (aCGH)Analysis of copy number alterations in the genome (comparison with a reference genome/sample)
Epigenomics/TranscriptomicsDNA/RNAWhole or targeted DNA methylationIdentification of disfunctions in regulatory elements
Whole or targeted miRNASequencing or detection of differential expression of miRNA
Whole or targeted long noncoding RNASequencing or detection of differential expression of long noncoding RNA
Whole or targeted mRNASequencing or detection of differential expression of coding genes