Characteristic | Total (N = 105) N (%) | 12-Month (N = 71) N (%) | No 12-Month (N = 34) N (%) | p-value |
---|---|---|---|---|
Male | 86 (81.9) | 57 (80.3) | 29 (85.3) | 0.526 |
White | 88 (83.8) | 63 (88.7) | 25 (73.5) | 0.054 |
Primary Site | ||||
Larynx | 38 (36.2) | 20 (28.2) | 18 (52.9) | 0.014 |
Pharynx | 67 (63.8) | 51 (71.8) | 16 (47.1) | |
T-Stage | ||||
I-II | 43 (41.0) | 34 (47.9) | 9 (26.5) | 0.034 |
III-IV | 62 (59.0) | 37 (52.1) | 25 (73.5) | |
N-Stage | ||||
0–1 | 45 (42.9) | 30 (42.3) | 15 (44.1) | 0.857 |
2–3 | 60 (57.1) | 41 (57.7) | 19 (55.9) | |
Surgery dissection (primary site) | 14 (13.3) | 5 (7.0) | 9 (26.5) | 0.008 |
Cell differentiationa | ||||
Poorly | 35 (38.5) | 28 (43.8) | 7 (25.9) | 0.179 |
Moderately | 48 (52.7) | 32 (50.0) | 16 (59.3) | |
Well | 8 (8.8) | 4 (6.3) | 4 (14.8) | |
Best overall responseb | ||||
Progressive disease | 4 (4.3) | 2 (2.9) | 2 (7.7) | < 0.001 |
Stable disease | 22 (23.4) | 7 (10.3) | 15 (57.7) | |
Partial response | 32 (34.0) | 27 (39.7) | 5 (19.2) | |
Complete response | 36 (38.3) | 32 (47.1) | 4 (15.4) | |
Weight lossc (previous 6 months) | ||||
> 10% body weight | 12 (12.2) | 6 (9.2) | 6 (18.2) | 0.288 |
5–10% body weight | 18 (18.4) | 14 (21.5) | 4 (12.1) | |
< 5% body weight | 68 (69.4) | 45 (69.2) | 23 (69.7) | |
Performance Status | ||||
Fully active | 50 (47.6) | 40 (80.0) | 10 (20.0) | 0.035 |
Strenuous restricted | 48 (45.7) | 27 (56.3) | 21 (43.8) | |
All self-care | 7 (6.7) | 4 (57.1) | 3 (42.9) | |
Time to survival (months) | ||||
> = 24 | 63 (61.8) | 52 (75.4) | 11 (33.3) | < 0.001 |
12–23 | 26 (25.5) | 17 (24.6) | 9 (27.3) | |
3–11 | 11 (10.8) | 0 (0.0) | 11 (33.3) | |
< 3 | 2 (2.0) | 0 (0.0) | 2 (6.1) | |
Mean (SD) | Mean (SD) | Mean (SD) | ||
Age | 58.9 (10.7) | 57.9 (9.7) | 60.9 (12.5) | 0.198 |