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Table 1 Demographic and clinical characteristics of the patients with and without 12-month assessments

From: ECOG-ACRIN 2399: analysis of patient related outcomes after Chemoradiation for locally advanced head and neck Cancer

Characteristic

Total

(N = 105)

N (%)

12-Month

(N = 71)

N (%)

No 12-Month

(N = 34)

N (%)

p-value

Male

86 (81.9)

57 (80.3)

29 (85.3)

0.526

White

88 (83.8)

63 (88.7)

25 (73.5)

0.054

Primary Site

 Larynx

38 (36.2)

20 (28.2)

18 (52.9)

0.014

 Pharynx

67 (63.8)

51 (71.8)

16 (47.1)

 

T-Stage

 I-II

43 (41.0)

34 (47.9)

9 (26.5)

0.034

 III-IV

62 (59.0)

37 (52.1)

25 (73.5)

 

N-Stage

 0–1

45 (42.9)

30 (42.3)

15 (44.1)

0.857

 2–3

60 (57.1)

41 (57.7)

19 (55.9)

 

Surgery dissection (primary site)

14 (13.3)

5 (7.0)

9 (26.5)

0.008

Cell differentiationa

 Poorly

35 (38.5)

28 (43.8)

7 (25.9)

0.179

 Moderately

48 (52.7)

32 (50.0)

16 (59.3)

 

 Well

8 (8.8)

4 (6.3)

4 (14.8)

 

Best overall responseb

 Progressive disease

4 (4.3)

2 (2.9)

2 (7.7)

< 0.001

 Stable disease

22 (23.4)

7 (10.3)

15 (57.7)

 

 Partial response

32 (34.0)

27 (39.7)

5 (19.2)

 

 Complete response

36 (38.3)

32 (47.1)

4 (15.4)

 

Weight lossc

(previous 6 months)

  > 10% body weight

12 (12.2)

6 (9.2)

6 (18.2)

0.288

 5–10% body weight

18 (18.4)

14 (21.5)

4 (12.1)

 

  < 5% body weight

68 (69.4)

45 (69.2)

23 (69.7)

 

Performance Status

 Fully active

50 (47.6)

40 (80.0)

10 (20.0)

0.035

 Strenuous restricted

48 (45.7)

27 (56.3)

21 (43.8)

 

 All self-care

7 (6.7)

4 (57.1)

3 (42.9)

 

Time to survival (months)

  > = 24

63 (61.8)

52 (75.4)

11 (33.3)

< 0.001

 12–23

26 (25.5)

17 (24.6)

9 (27.3)

 

 3–11

11 (10.8)

0 (0.0)

11 (33.3)

 

  < 3

2 (2.0)

0 (0.0)

2 (6.1)

 
 

Mean (SD)

Mean (SD)

Mean (SD)

 

Age

58.9 (10.7)

57.9 (9.7)

60.9 (12.5)

0.198

  1. a N = 91; b N = 94; c N = 98