Skip to main content

Table 1 Demographic and clinical characteristics of the patients with and without 12-month assessments

From: ECOG-ACRIN 2399: analysis of patient related outcomes after Chemoradiation for locally advanced head and neck Cancer

Characteristic Total
(N = 105)
N (%)
12-Month
(N = 71)
N (%)
No 12-Month
(N = 34)
N (%)
p-value
Male 86 (81.9) 57 (80.3) 29 (85.3) 0.526
White 88 (83.8) 63 (88.7) 25 (73.5) 0.054
Primary Site
 Larynx 38 (36.2) 20 (28.2) 18 (52.9) 0.014
 Pharynx 67 (63.8) 51 (71.8) 16 (47.1)  
T-Stage
 I-II 43 (41.0) 34 (47.9) 9 (26.5) 0.034
 III-IV 62 (59.0) 37 (52.1) 25 (73.5)  
N-Stage
 0–1 45 (42.9) 30 (42.3) 15 (44.1) 0.857
 2–3 60 (57.1) 41 (57.7) 19 (55.9)  
Surgery dissection (primary site) 14 (13.3) 5 (7.0) 9 (26.5) 0.008
Cell differentiationa
 Poorly 35 (38.5) 28 (43.8) 7 (25.9) 0.179
 Moderately 48 (52.7) 32 (50.0) 16 (59.3)  
 Well 8 (8.8) 4 (6.3) 4 (14.8)  
Best overall responseb
 Progressive disease 4 (4.3) 2 (2.9) 2 (7.7) < 0.001
 Stable disease 22 (23.4) 7 (10.3) 15 (57.7)  
 Partial response 32 (34.0) 27 (39.7) 5 (19.2)  
 Complete response 36 (38.3) 32 (47.1) 4 (15.4)  
Weight lossc
(previous 6 months)
  > 10% body weight 12 (12.2) 6 (9.2) 6 (18.2) 0.288
 5–10% body weight 18 (18.4) 14 (21.5) 4 (12.1)  
  < 5% body weight 68 (69.4) 45 (69.2) 23 (69.7)  
Performance Status
 Fully active 50 (47.6) 40 (80.0) 10 (20.0) 0.035
 Strenuous restricted 48 (45.7) 27 (56.3) 21 (43.8)  
 All self-care 7 (6.7) 4 (57.1) 3 (42.9)  
Time to survival (months)
  > = 24 63 (61.8) 52 (75.4) 11 (33.3) < 0.001
 12–23 26 (25.5) 17 (24.6) 9 (27.3)  
 3–11 11 (10.8) 0 (0.0) 11 (33.3)  
  < 3 2 (2.0) 0 (0.0) 2 (6.1)  
  Mean (SD) Mean (SD) Mean (SD)  
Age 58.9 (10.7) 57.9 (9.7) 60.9 (12.5) 0.198
  1. a N = 91; b N = 94; c N = 98