Table 2 Multivariate Analysis of Overall and Disease-Free Survival

1.02

0.993–1.05

0.148

T stage

T3-T4 vs. T0-T2

1.84

0.960–3.53

0.0661

N stage

N2b-N3 vs. N0-N2a

4.63

2.43–8.82

3.16E-06

HPV

Positive vs. negative

2.42

0.817–7.19

0.1107

TP53

Mutant vs. wildtype

1.96

1.06–3.60

0.0311

Variable

Comparison

Hazard Ratio

95% CI

HR p-value

Gender

Male vs. Female

2.98

1.27–7.01

0.0122

N stage

N2b-N3 vs. N0-N2a

3.12

1.52–6.40

0.00188

HPV

Positive vs Negative

2.25

0.847–5.96

0.104

Adjuvant Chemotherapy

Yes vs. No

1.77

0.885–3.52

0.107