TY - JOUR AU - Dalla Torre, D. AU - Burtscher, D. AU - Soelder, E. AU - Offermanns, V. AU - Rasse, M. AU - Puelacher, W. PY - 2018 DA - 2018// TI - Human papillomavirus prevalence in a mid-European oral squamous cell cancer population: a cohort study JO - Oral Dis VL - 24 UR - https://doi.org/10.1111/odi.12882 DO - 10.1111/odi.12882 ID - Dalla Torre2018 ER - TY - JOUR AU - Götz, C. AU - Drecoll, E. AU - Straub, M. AU - Bissinger, O. AU - Wolff, K. -. D. AU - Kolk, A. PY - 2016 DA - 2016// TI - Impact of HPV infection on oral squamous cell carcinoma JO - Oncotarget VL - 7 UR - https://doi.org/10.18632/oncotarget.12501 DO - 10.18632/oncotarget.12501 ID - Götz2016 ER - TY - JOUR AU - Shiboski, C. H. AU - Schmidt, B. L. AU - Jordan, R. C. K. PY - 2005 DA - 2005// TI - Tongue and tonsil carcinoma: increasing trends in the U.S. population ages 20-44 years JO - Cancer VL - 103 UR - https://doi.org/10.1002/cncr.20998 DO - 10.1002/cncr.20998 ID - Shiboski2005 ER - TY - JOUR AU - Frisch, M. AU - Hjalgrim, H. AU - Jaeger, A. B. AU - Biggar, R. J. PY - 2000 DA - 2000// TI - Changing patterns of tonsillar squamous cell carcinoma in the United States JO - Cancer Causes Control CCC VL - 11 UR - https://doi.org/10.1023/A:1008918223334 DO - 10.1023/A:1008918223334 ID - Frisch2000 ER - TY - JOUR AU - Mehta, V. AU - Yu, G. -. P. AU - Schantz, S. P. PY - 2010 DA - 2010// TI - Population-based analysis of oral and oropharyngeal carcinoma: changing trends of histopathologic differentiation, survival and patient demographics JO - Laryngoscope VL - 120 UR - https://doi.org/10.1002/lary.21129 DO - 10.1002/lary.21129 ID - Mehta2010 ER - TY - JOUR AU - Sturgis, E. M. AU - Cinciripini, P. M. PY - 2007 DA - 2007// TI - Trends in head and neck cancer incidence in relation to smoking prevalence JO - Cancer VL - 110 UR - https://doi.org/10.1002/cncr.22963. DO - 10.1002/cncr.22963. ID - Sturgis2007 ER - TY - JOUR AU - Chaturvedi, A. K. AU - Engels, E. A. AU - Pfeiffer, R. M. AU - Hernandez, B. Y. AU - Xiao, W. AU - Kim, E. PY - 2011 DA - 2011// TI - Human papillomavirus and rising oropharyngeal Cancer incidence in the United States JO - J Clin Oncol VL - 29 UR - https://doi.org/10.1200/JCO.2011.36.4596 DO - 10.1200/JCO.2011.36.4596 ID - Chaturvedi2011 ER - TY - JOUR AU - Steinau, M. AU - Saraiya, M. AU - Goodman, M. T. AU - Peters, E. S. AU - Watson, M. AU - Cleveland, J. L. PY - 2014 DA - 2014// TI - Human papillomavirus prevalence in oropharyngeal cancer before vaccine introduction, United States JO - Emerg Infect Dis VL - 20 UR - https://doi.org/10.3201/eid2005.131311 DO - 10.3201/eid2005.131311 ID - Steinau2014 ER - TY - JOUR AU - Singhi, A. D. AU - Westra, W. H. PY - 2010 DA - 2010// TI - Comparison of human papillomavirus in situ hybridization and p16 immunohistochemistry in the detection of human papillomavirus-associated head and neck cancer based on a prospective clinical experience JO - Cancer VL - 116 ID - Singhi2010 ER - TY - STD TI - CDC - How Many Cancers Are Linked with HPV Each Year? https://www.cdc.gov/cancer/hpv/statistics/cases.htm. Accessed 15 Mar 2018. UR - https://www.cdc.gov/cancer/hpv/statistics/cases.htm ID - ref10 ER - TY - JOUR AU - Pytynia, K. B. AU - Dahlstrom, K. R. AU - Sturgis, E. M. PY - 2014 DA - 2014// TI - Epidemiology of HPV-associated oropharyngeal cancer JO - Oral Oncol VL - 50 UR - https://doi.org/10.1016/j.oraloncology.2013.12.019 DO - 10.1016/j.oraloncology.2013.12.019 ID - Pytynia2014 ER - TY - JOUR AU - Gillison, M. L. PY - 2007 DA - 2007// TI - Current topics in the epidemiology of oral cavity and oropharyngeal cancers JO - Head Neck VL - 29 UR - https://doi.org/10.1002/hed.20573 DO - 10.1002/hed.20573 ID - Gillison2007 ER - TY - JOUR AU - Goon, P. K. C. AU - Stanley, M. A. AU - Ebmeyer, J. AU - Steinsträsser, L. AU - Upile, T. AU - Jerjes, W. PY - 2009 DA - 2009// TI - HPV & head and neck cancer: a descriptive update JO - Head Neck Oncol VL - 1 UR - https://doi.org/10.1186/1758-3284-1-36 DO - 10.1186/1758-3284-1-36 ID - Goon2009 ER - TY - JOUR AU - Gillison, M. L. AU - Koch, W. M. AU - Capone, R. B. AU - Spafford, M. AU - Westra, W. H. AU - Wu, L. PY - 2000 DA - 2000// TI - Evidence for a causal association between human papillomavirus and a subset of head and neck cancers JO - J Natl Cancer Inst VL - 92 UR - https://doi.org/10.1093/jnci/92.9.709 DO - 10.1093/jnci/92.9.709 ID - Gillison2000 ER - TY - JOUR AU - Dahlstrom, K. R. AU - Calzada, G. AU - Hanby, J. D. AU - Garden, A. S. AU - Glisson, B. S. AU - Li, G. PY - 2013 DA - 2013// TI - an evolution in demographics, treatment, and outcomes of oropharyngeal cancer at a major cancer center JO - Cancer VL - 119 UR - https://doi.org/10.1002/cncr.27727. DO - 10.1002/cncr.27727. ID - Dahlstrom2013 ER - TY - JOUR AU - Chaturvedi, A. K. AU - Engels, E. A. AU - Anderson, W. F. AU - Gillison, M. L. PY - 2008 DA - 2008// TI - Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States JO - J Clin Oncol Off J Am Soc Clin Oncol VL - 26 UR - https://doi.org/10.1200/JCO.2007.14.1713 DO - 10.1200/JCO.2007.14.1713 ID - Chaturvedi2008 ER - TY - JOUR AU - Gillison, M. L. AU - Chaturvedi, A. K. AU - Anderson, W. F. AU - Fakhry, C. PY - 2015 DA - 2015// TI - Epidemiology of human papillomavirus–positive head and neck squamous cell carcinoma JO - J Clin Oncol VL - 33 UR - https://doi.org/10.1200/JCO.2015.61.6995 DO - 10.1200/JCO.2015.61.6995 ID - Gillison2015 ER - TY - JOUR AU - Gillison, M. L. AU - Alemany, L. AU - Snijders, P. J. F. AU - Chaturvedi, A. AU - Steinberg, B. M. AU - Schwartz, S. PY - 2012 DA - 2012// TI - Human papillomavirus and diseases of the upper airway: head and neck cancer and respiratory papillomatosis JO - Vaccine VL - 30 UR - https://doi.org/10.1016/j.vaccine.2012.05.070 DO - 10.1016/j.vaccine.2012.05.070 ID - Gillison2012 ER - TY - JOUR AU - Gillison, M. L. AU - Broutian, T. AU - Pickard, R. K. L. AU - Tong, Z. AU - Xiao, W. AU - Kahle, L. PY - 2012 DA - 2012// TI - Prevalence of oral HPV infection in the United States, 2009-2010 JO - JAMA VL - 307 UR - https://doi.org/10.1001/jama.2012.101 DO - 10.1001/jama.2012.101 ID - Gillison2012 ER - TY - JOUR AU - D’Souza, G. AU - Agrawal, Y. AU - Halpern, J. AU - Bodison, S. AU - Gillison, M. L. PY - 2009 DA - 2009// TI - Oral sexual behaviors associated with prevalent Oral human papillomavirus infection JO - J Infect Dis VL - 199 UR - https://doi.org/10.1086/597755 DO - 10.1086/597755 ID - D’Souza2009 ER - TY - JOUR AU - Kjaer, S. K. AU - Chackerian, B. AU - Brule, A. J. AU - Svare, E. I. AU - Paull, G. AU - Walbomers, J. M. PY - 2001 DA - 2001// TI - High-risk human papillomavirus is sexually transmitted: evidence from a follow-up study of virgins starting sexual activity (intercourse). Cancer Epidemiol biomark Prev Publ am Assoc Cancer res cosponsored am Soc Prev JO - Oncologia VL - 10 ID - Kjaer2001 ER - TY - STD TI - Clinician FAQs: CDC Recommendations for HPV Vaccine 2-Dose Schedule | Human Papillomavirus (HPV) | CDC. 2017. https://www.cdc.gov/hpv/hcp/2-dose/clinician-faq.html. Accessed 24 Feb 2018. UR - https://www.cdc.gov/hpv/hcp/2-dose/clinician-faq.html ID - ref22 ER - TY - JOUR AU - Chaturvedi, A. K. AU - Graubard, B. I. AU - Broutian, T. AU - Pickard, R. K. L. AU - Tong, Z. -. Y. AU - Xiao, W. PY - 2017 DA - 2017// TI - Effect of Prophylactic Human Papillomavirus (HPV) Vaccination on Oral HPV Infections Among Young Adults in the United States JO - J Clin Oncol VL - 36 UR - https://doi.org/10.1200/JCO.2017.75.0141 DO - 10.1200/JCO.2017.75.0141 ID - Chaturvedi2017 ER - TY - STD TI - DG Pfister, S Spencer. NCCN clinical practice guidelines in oncology: head and neck cancers (version 1. 2018). https://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed 11 Feb 2018. UR - https://www.nccn.org/professionals/physician_gls/f_guidelines.asp ID - ref24 ER - TY - JOUR AU - Thavaraj, S. AU - Stokes, A. AU - Guerra, E. AU - Bible, J. AU - Halligan, E. AU - Long, A. PY - 2011 DA - 2011// TI - Evaluation of human papillomavirus testing for squamous cell carcinoma of the tonsil in clinical practice JO - J Clin Pathol VL - 64 UR - https://doi.org/10.1136/jcp.2010.088450 DO - 10.1136/jcp.2010.088450 ID - Thavaraj2011 ER - TY - JOUR AU - Schache, A. G. AU - Liloglou, T. AU - Risk, J. M. AU - Filia, A. AU - Jones, T. M. AU - Sheard, J. PY - 2011 DA - 2011// TI - Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: sensitivity, specificity, and prognostic discrimination JO - Clin Cancer Res VL - 17 UR - https://doi.org/10.1158/1078-0432.CCR-11-0388 DO - 10.1158/1078-0432.CCR-11-0388 ID - Schache2011 ER - TY - JOUR AU - Reed, A. L. AU - Califano, J. AU - Cairns, P. AU - Westra, W. H. AU - Jones, R. M. AU - Koch, W. PY - 1996 DA - 1996// TI - High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma JO - Cancer Res VL - 56 ID - Reed1996 ER - TY - JOUR AU - Wasylyk, B. AU - Abecassis, J. AU - Jung, A. C. PY - 2013 DA - 2013// TI - Identification of clinically relevant HPV-related HNSCC: in p16 should we trust? JO - Oral Oncol VL - 49 UR - https://doi.org/10.1016/j.oraloncology.2013.07.014 DO - 10.1016/j.oraloncology.2013.07.014 ID - Wasylyk2013 ER - TY - JOUR AU - Bishop, J. A. AU - Lewis, J. S. AU - Rocco, J. W. AU - Faquin, W. C. PY - 2015 DA - 2015// TI - HPV-related squamous cell carcinoma of the head and neck: an update on testing in routine pathology practice JO - Semin Diagn Pathol VL - 32 UR - https://doi.org/10.1053/j.semdp.2015.02.013 DO - 10.1053/j.semdp.2015.02.013 ID - Bishop2015 ER - TY - STD TI - Cancer of the upper aerodigestive tract: assessment and management in people aged 16 and over | Guidance and guidelines | NICE. https://www.nice.org.uk/guidance/NG36/chapter/Recommendations#hpvrelated-disease. Accessed 11 Feb 2018. UR - https://www.nice.org.uk/guidance/NG36/chapter/Recommendations#hpvrelated-disease ID - ref30 ER - TY - JOUR AU - Baldassarri, R. AU - Aronberg, R. AU - Levi, A. W. AU - Yarbrough, W. G. AU - Kowalski, D. AU - Chhieng, D. PY - 2015 DA - 2015// TI - Detection and genotype of high-Risk human papillomavirus in fine-needle aspirates of patients with metastatic squamous cell carcinoma is helpful in determining tumor origin JO - Am J Clin Pathol VL - 143 UR - https://doi.org/10.1309/AJCPCZA4PSZCFHQ4 DO - 10.1309/AJCPCZA4PSZCFHQ4 ID - Baldassarri2015 ER - TY - JOUR AU - Parfenov, M. AU - Pedamallu, C. S. AU - Gehlenborg, N. AU - Freeman, S. S. AU - Danilova, L. AU - Bristow, C. A. PY - 2014 DA - 2014// TI - Characterization of HPV and host genome interactions in primary head and neck cancers JO - Proc Natl Acad Sci VL - 111 UR - https://doi.org/10.1073/pnas.1416074111 DO - 10.1073/pnas.1416074111 ID - Parfenov2014 ER - TY - JOUR AU - Ang, K. K. AU - Harris, J. AU - Wheeler, R. AU - Weber, R. AU - Rosenthal, D. I. AU - Nguyen-Tân, P. F. PY - 2010 DA - 2010// TI - Human papillomavirus and survival of patients with oropharyngeal Cancer JO - N Engl J Med VL - 363 UR - https://doi.org/10.1056/NEJMoa0912217 DO - 10.1056/NEJMoa0912217 ID - Ang2010 ER - TY - JOUR AU - Fakhry, C. AU - Westra, W. H. AU - Li, S. AU - Cmelak, A. AU - Ridge, J. A. AU - Pinto, H. PY - 2008 DA - 2008// TI - Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial JO - J Natl Cancer Inst VL - 100 UR - https://doi.org/10.1093/jnci/djn011 DO - 10.1093/jnci/djn011 ID - Fakhry2008 ER - TY - STD TI - Amin MB, Edge S, Greene F, Byrd DR, Brookland RK, Washington MK, et al. In: AJCC, editor. Cancer Staging Manual. 8th ed: Springer International Publishing; 2017. www.springer.com/us/book/9783319406176. Accessed 27 Feb 2018. UR - http://www.springer.com/us/book/9783319406176 ID - ref35 ER - TY - JOUR AU - Lewis, J. S. AU - Thorstad, W. L. AU - Chernock, R. D. AU - Haughey, B. H. AU - Yip, J. H. AU - Zhang, Q. PY - 2010 DA - 2010// TI - p16 positive oropharyngeal squamous cell carcinoma: an entity with a favorable prognosis regardless of tumor HPV status JO - Am J Surg Pathol VL - 34 UR - https://doi.org/10.1097/PAS.0b013e3181e84652 DO - 10.1097/PAS.0b013e3181e84652 ID - Lewis2010 ER - TY - JOUR AU - Albers, A. E. AU - Qian, X. AU - Kaufmann, A. M. AU - Coordes, A. PY - 2017 DA - 2017// TI - Meta analysis: HPV and p16 pattern determines survival in patients with HNSCC and identifies potential new biologic subtype JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/s41598-017-16918-w DO - 10.1038/s41598-017-16918-w ID - Albers2017 ER - TY - JOUR AU - Hajek, M. AU - Sewell, A. AU - Kaech, S. AU - Burtness, B. AU - Yarbrough, W. G. AU - Issaeva, N. PY - 2017 DA - 2017// TI - TRAF3/CYLD mutations identify a distinct subset of human papillomavirus-associated head and neck squamous cell carcinoma JO - Cancer VL - 123 UR - https://doi.org/10.1002/cncr.30570 DO - 10.1002/cncr.30570 ID - Hajek2017 ER - TY - JOUR AU - Pan, C. AU - Yarbrough, W. G. AU - Issaeva, N. PY - 2018 DA - 2018// TI - Advances in biomarkers and treatment strategies for HPV-associated head and neck cancer JO - Oncoscience VL - 5 ID - Pan2018 ER - TY - JOUR AU - Budach, W. AU - Bölke, E. AU - Kammers, K. AU - Gerber, P. A. AU - Orth, K. AU - Gripp, S. PY - 2016 DA - 2016// TI - Induction chemotherapy followed by concurrent radio-chemotherapy versus concurrent radio-chemotherapy alone as treatment of locally advanced squamous cell carcinoma of the head and neck (HNSCC): a meta-analysis of randomized trials JO - Radiother Oncol J Eur Soc Ther Radiol Oncol VL - 118 UR - https://doi.org/10.1016/j.radonc.2015.10.014 DO - 10.1016/j.radonc.2015.10.014 ID - Budach2016 ER - TY - JOUR AU - Forastiere, A. A. AU - Zhang, Q. AU - Weber, R. S. AU - Maor, M. H. AU - Goepfert, H. AU - Pajak, T. F. PY - 2013 DA - 2013// TI - Long-term results of RTOG 91-11: a comparison of three nonsurgical treatment strategies to preserve the larynx in patients with locally advanced larynx cancer JO - J Clin Oncol Off J Am Soc Clin Oncol VL - 31 UR - https://doi.org/10.1200/JCO.2012.43.6097 DO - 10.1200/JCO.2012.43.6097 ID - Forastiere2013 ER - TY - JOUR AU - Marur, S. AU - Li, S. AU - Cmelak, A. J. AU - Gillison, M. L. AU - Zhao, W. J. AU - Ferris, R. L. PY - 2017 DA - 2017// TI - E1308: phase II trial of induction chemotherapy followed by reduced-dose radiation and weekly Cetuximab in patients with HPV-associated Resectable squamous cell carcinoma of the oropharynx- ECOG-ACRIN Cancer research group JO - J Clin Oncol Off J Am Soc Clin Oncol VL - 35 UR - https://doi.org/10.1200/JCO.2016.68.3300 DO - 10.1200/JCO.2016.68.3300 ID - Marur2017 ER - TY - JOUR AU - Chen, A. M. AU - Felix, C. AU - Wang, P. -. C. AU - Hsu, S. AU - Basehart, V. AU - Garst, J. PY - 2017 DA - 2017// TI - Reduced-dose radiotherapy for human papillomavirus-associated squamous-cell carcinoma of the oropharynx: a single-arm, phase 2 study JO - Lancet Oncol VL - 18 UR - https://doi.org/10.1016/S1470-2045(17)30246-2 DO - 10.1016/S1470-2045(17)30246-2 ID - Chen2017 ER - TY - JOUR AU - Biktasova, A. AU - Hajek, M. AU - Sewell, A. AU - Gary, C. AU - Bellinger, G. AU - Deshpande, H. A. PY - 2017 DA - 2017// TI - Demethylation therapy as a targeted treatment for human papillomavirus–associated head and neck Cancer JO - Clin Cancer Res VL - 23 UR - https://doi.org/10.1158/1078-0432.CCR-17-1438 DO - 10.1158/1078-0432.CCR-17-1438 ID - Biktasova2017 ER - TY - JOUR AU - Saleh, K. AU - Eid, R. AU - Haddad, F. G. AU - Khalife-Saleh, N. AU - Kourie, H. R. PY - 2018 DA - 2018// TI - New developments in the management of head and neck cancer - impact of pembrolizumab JO - Ther Clin Risk Manag VL - 14 UR - https://doi.org/10.2147/TCRM.S125059 DO - 10.2147/TCRM.S125059 ID - Saleh2018 ER - TY - JOUR AU - Lyford-Pike, S. AU - Peng, S. AU - Young, G. D. AU - Taube, J. M. AU - Westra, W. H. AU - Akpeng, B. PY - 2013 DA - 2013// TI - Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma JO - Cancer Res VL - 73 UR - https://doi.org/10.1158/0008-5472.CAN-12-2384 DO - 10.1158/0008-5472.CAN-12-2384 ID - Lyford-Pike2013 ER - TY - STD TI - Pembrolizumab (KEYTRUDA). https://www.fda.gov/drugs/informationondrugs/approveddrugs/ucm515627.htm. Accessed 21 Mar 2018. UR - https://www.fda.gov/drugs/informationondrugs/approveddrugs/ucm515627.htm ID - ref47 ER - TY - STD TI - Nivolumab for SCCHN. https://www.fda.gov/drugs/informationondrugs/approveddrugs/ucm528920.htm. Accessed 21 Mar 2018. UR - https://www.fda.gov/drugs/informationondrugs/approveddrugs/ucm528920.htm ID - ref48 ER - TY - STD TI - ClinicalTrials.gov. https://www.clinicaltrials.gov/. Accessed 21 Mar 2018. UR - https://www.clinicaltrials.gov ID - ref49 ER - TY - JOUR PY - 2015 DA - 2015// TI - Comprehensive genomic characterization of head and neck squamous cell carcinomas JO - Nature VL - 517 UR - https://doi.org/10.1038/nature14129 DO - 10.1038/nature14129 ID - ref50 ER - TY - JOUR AU - Stransky, N. AU - Egloff, A. M. AU - Tward, A. D. AU - Kostic, A. D. AU - Cibulskis, K. AU - Sivachenko, A. PY - 2011 DA - 2011// TI - The mutational landscape of head and neck squamous cell carcinoma JO - Science VL - 333 UR - https://doi.org/10.1126/science.1208130 DO - 10.1126/science.1208130 ID - Stransky2011 ER - TY - JOUR AU - Agrawal, N. AU - Frederick, M. J. AU - Pickering, C. R. AU - Bettegowda, C. AU - Chang, K. AU - Li, R. J. PY - 2011 DA - 2011// TI - Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1 JO - Science VL - 333 UR - https://doi.org/10.1126/science.1206923 DO - 10.1126/science.1206923 ID - Agrawal2011 ER - TY - JOUR AU - Mirghani, H. AU - Amen, F. AU - Tao, Y. AU - Deutsch, E. AU - Levy, A. PY - 2015 DA - 2015// TI - Increased radiosensitivity of HPV-positive head and neck cancers: molecular basis and therapeutic perspectives JO - Cancer Treat Rev VL - 41 UR - https://doi.org/10.1016/j.ctrv.2015.10.001 DO - 10.1016/j.ctrv.2015.10.001 ID - Mirghani2015 ER - TY - JOUR AU - Brumbaugh, K. M. AU - Otterness, D. M. AU - Geisen, C. AU - Oliveira, V. AU - Brognard, J. AU - Li, X. PY - 2004 DA - 2004// TI - The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells JO - Mol Cell VL - 14 UR - https://doi.org/10.1016/j.molcel.2004.05.005 DO - 10.1016/j.molcel.2004.05.005 ID - Brumbaugh2004 ER - TY - JOUR AU - Gewandter, J. S. AU - Bambara, R. A. AU - O’Reilly, M. A. PY - 2011 DA - 2011// TI - The RNA surveillance protein SMG1 activates p53 in response to DNA double-strand breaks but not exogenously oxidized mRNA JO - Cell Cycle VL - 10 UR - https://doi.org/10.4161/cc.10.15.16347 DO - 10.4161/cc.10.15.16347 ID - Gewandter2011 ER - TY - JOUR AU - Shiloh, Y. PY - 2003 DA - 2003// TI - ATM and related protein kinases: safeguarding genome integrity JO - Nat Rev Cancer VL - 3 UR - https://doi.org/10.1038/nrc1011 DO - 10.1038/nrc1011 ID - Shiloh2003 ER - TY - JOUR AU - Gubanova, E. AU - Brown, B. AU - Ivanov, S. V. AU - Helleday, T. AU - Mills, G. B. AU - Yarbrough, W. G. PY - 2012 DA - 2012// TI - Downregulation of SMG-1 in HPV-positive head and neck squamous cell carcinoma due to promoter hypermethylation correlates with improved survival JO - Clin Cancer res off J am Assoc Cancer Res VL - 18 UR - https://doi.org/10.1158/1078-0432.CCR-11-2058 DO - 10.1158/1078-0432.CCR-11-2058 ID - Gubanova2012 ER - TY - JOUR AU - Sewell, A. AU - Brown, B. AU - Biktasova, A. AU - Mills, G. B. AU - Lu, Y. AU - Tyson, D. R. PY - 2014 DA - 2014// TI - Reverse-phase protein array profiling of oropharyngeal cancer and significance of PIK3CA mutations in HPV-associated head and neck cancer JO - Clin Cancer Res Off J Am Assoc Cancer Res. VL - 20 UR - https://doi.org/10.1158/1078-0432.CCR-13-2585 DO - 10.1158/1078-0432.CCR-13-2585 ID - Sewell2014 ER - TY - JOUR AU - Dok, R. AU - Kalev, P. AU - Limbergen, E. J. AU - Asbagh, L. A. AU - Vázquez, I. AU - Hauben, E. PY - 2014 DA - 2014// TI - p16INK4a impairs homologous recombination-mediated DNA repair in human papillomavirus-positive head and neck tumors JO - Cancer Res VL - 74 UR - https://doi.org/10.1158/0008-5472.CAN-13-2479 DO - 10.1158/0008-5472.CAN-13-2479 ID - Dok2014 ER - TY - JOUR AU - Weaver, A. N. AU - Cooper, T. S. AU - Rodriguez, M. AU - Trummell, H. Q. AU - Bonner, J. A. AU - Rosenthal, E. L. PY - 2015 DA - 2015// TI - DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma JO - Oncotarget VL - 6 UR - https://doi.org/10.18632/oncotarget.4863 DO - 10.18632/oncotarget.4863 ID - Weaver2015 ER - TY - JOUR AU - Slebos, R. J. C. AU - Jehmlich, N. AU - Brown, B. AU - Yin, Z. AU - Chung, C. H. AU - Yarbrough, W. G. PY - 2013 DA - 2013// TI - Proteomic analysis of oropharyngeal carcinomas reveals novel HPV-associated biological pathways JO - Int J Cancer J Int Cancer VL - 132 UR - https://doi.org/10.1002/ijc.27699 DO - 10.1002/ijc.27699 ID - Slebos2013 ER - TY - JOUR AU - Gary, C. AU - Hajek, M. AU - Biktasova, A. AU - Bellinger, G. AU - Yarbrough, W. G. AU - Issaeva, N. PY - 2016 DA - 2016// TI - Selective antitumor activity of roscovitine in head and neck cancer JO - Oncotarget VL - 7 UR - https://doi.org/10.18632/oncotarget.9560 DO - 10.18632/oncotarget.9560 ID - Gary2016 ER - TY - JOUR AU - Zhang, Y. AU - Koneva, L. A. AU - Virani, S. AU - Arthur, A. E. AU - Virani, A. AU - Hall, P. B. PY - 2016 DA - 2016// TI - Subtypes of HPV-positive head and neck cancers are associated with HPV characteristics, copy number alterations, PIK3CA mutation, and pathway signatures JO - Clin Cancer Res Off J Am Assoc Cancer Res VL - 22 UR - https://doi.org/10.1158/1078-0432.CCR-16-0323 DO - 10.1158/1078-0432.CCR-16-0323 ID - Zhang2016 ER - TY - JOUR AU - Muñoz, N. AU - Castellsagué, X. AU - González, A. B. AU - Gissmann, L. PY - 2006 DA - 2006// TI - Chapter 1: HPV in the etiology of human cancer JO - Vaccine VL - 24 UR - https://doi.org/10.1016/j.vaccine.2006.05.115. DO - 10.1016/j.vaccine.2006.05.115. ID - Muñoz2006 ER - TY - JOUR AU - Koneva, L. A. AU - Zhang, Y. AU - Virani, S. AU - Hall, P. B. AU - McHugh, J. B. AU - Chepeha, D. B. PY - 2018 DA - 2018// TI - HPV integration in HNSCC correlates with survival outcomes, immune response signatures, and candidate drivers JO - Mol Cancer Res MCR VL - 16 UR - https://doi.org/10.1158/1541-7786.MCR-17-0153 DO - 10.1158/1541-7786.MCR-17-0153 ID - Koneva2018 ER - TY - JOUR AU - Berman Tara, A. AU - Schiller John, T. PY - 2017 DA - 2017// TI - Human papillomavirus in cervical cancer and oropharyngeal cancer: one cause JO - two diseases Cancer VL - 123 UR - https://doi.org/10.1002/cncr.30588. DO - 10.1002/cncr.30588. ID - Berman Tara2017 ER - TY - JOUR AU - Stanley, M. PY - 2010 DA - 2010// TI - Pathology and epidemiology of HPV infection in females JO - Gynecol Oncol VL - 117 UR - https://doi.org/10.1016/j.ygyno.2010.01.024 DO - 10.1016/j.ygyno.2010.01.024 ID - Stanley2010 ER - TY - JOUR AU - Nakahara, T. AU - Kiyono, T. PY - 2016 DA - 2016// TI - Interplay between NF-κB/interferon signaling and the genome replication of HPV JO - Future Virol VL - 11 UR - https://doi.org/10.2217/fvl.16.2 DO - 10.2217/fvl.16.2 ID - Nakahara2016 ER - TY - STD TI - Hong S, Laimins LA. Manipulation of the innate immune response by human papillomaviruses., manipulation of the innate immune response by human papillomaviruses. Virus res Virus Res 2017;231, 231:34, 34–240. doi:https://doi.org/10.1016/j.virusres.2016.11.004, https://doi.org/10.1016/j.virusres.2016.11.004. ID - ref69 ER - TY - JOUR AU - Thomas, M. AU - Narayan, N. AU - Pim, D. AU - Tomaić, V. AU - Massimi, P. AU - Nagasaka, K. PY - 2008 DA - 2008// TI - Human papillomaviruses, cervical cancer and cell polarity JO - Oncogene VL - 27 UR - https://doi.org/10.1038/onc.2008.351 DO - 10.1038/onc.2008.351 ID - Thomas2008 ER - TY - JOUR AU - Maglennon, G. A. AU - McIntosh, P. AU - Doorbar, J. PY - 2011 DA - 2011// TI - Persistence of viral DNA in the epithelial basal layer suggests a model for papillomavirus latency following immune regression JO - Virology VL - 414 UR - https://doi.org/10.1016/j.virol.2011.03.019 DO - 10.1016/j.virol.2011.03.019 ID - Maglennon2011 ER - TY - JOUR AU - Stanley, M. A. AU - Pett, M. R. AU - Coleman, N. PY - 2007 DA - 2007// TI - HPV: from infection to cancer JO - Biochem Soc Trans VL - 35 UR - https://doi.org/10.1042/BST0351456 DO - 10.1042/BST0351456 ID - Stanley2007 ER - TY - JOUR AU - Moscicki, A. -. B. AU - Schiffman, M. AU - Kjaer, S. AU - Villa, L. L. PY - 2006 DA - 2006// TI - Chapter 5: updating the natural history of HPV and anogenital cancer JO - Vaccine VL - 24 ID - Moscicki2006 ER - TY - JOUR AU - Lesseur, C. AU - Diergaarde, B. AU - Olshan, A. F. AU - Wünsch-Filho, V. AU - Ness, A. R. AU - Liu, G. PY - 2016 DA - 2016// TI - Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer JO - Nat Genet VL - 48 UR - https://doi.org/10.1038/ng.3685 DO - 10.1038/ng.3685 ID - Lesseur2016 ER - TY - JOUR AU - Cullen, A. P. AU - Reid, R. AU - Campion, M. AU - Lörincz, A. T. PY - 1991 DA - 1991// TI - Analysis of the physical state of different human papillomavirus DNAs in intraepithelial and invasive cervical neoplasm JO - J Virol VL - 65 ID - Cullen1991 ER - TY - JOUR AU - Hudelist, G. AU - Manavi, M. AU - Pischinger, K. I. D. AU - Watkins-Riedel, T. AU - Singer, C. F. AU - Kubista, E. PY - 2004 DA - 2004// TI - Physical state and expression of HPV DNA in benign and dysplastic cervical tissue: different levels of viral integration are correlated with lesion grade JO - Gynecol Oncol VL - 92 UR - https://doi.org/10.1016/j.ygyno.2003.11.035 DO - 10.1016/j.ygyno.2003.11.035 ID - Hudelist2004 ER - TY - JOUR AU - Woodman, C. B. J. AU - Collins, S. I. AU - Young, L. S. PY - 2007 DA - 2007// TI - The natural history of cervical HPV infection: unresolved issues JO - Nat Rev Cancer VL - 7 UR - https://doi.org/10.1038/nrc2050 DO - 10.1038/nrc2050 ID - Woodman2007 ER - TY - JOUR AU - Nulton, T. J. AU - Olex, A. L. AU - Dozmorov, M. AU - Morgan, I. M. AU - Windle, B. AU - Nulton, T. J. PY - 2017 DA - 2017// TI - Analysis of the Cancer genome atlas sequencing data reveals novel properties of the human papillomavirus 16 genome in head and neck squamous cell carcinoma JO - Oncotarget VL - 8 UR - https://doi.org/10.18632/oncotarget.15179 DO - 10.18632/oncotarget.15179 ID - Nulton2017 ER - TY - JOUR AU - Morgan, I. M. AU - DiNardo, L. J. AU - Windle, B. PY - 2017 DA - 2017// TI - Integration of human papillomavirus genomes in head and neck Cancer: is it time to consider a paradigm shift? JO - Viruses VL - 9 UR - https://doi.org/10.3390/v9080208 DO - 10.3390/v9080208 ID - Morgan2017 ER - TY - JOUR AU - Gelwan, E. AU - Malm, I. -. J. AU - Khararjian, A. AU - Fakhry, C. AU - Bishop, J. A. AU - Westra, W. H. PY - 2017 DA - 2017// TI - Nonuniform distribution of high-risk human papillomavirus in squamous cell carcinomas of the oropharynx: rethinking the anatomic boundaries of Oral and oropharyngeal carcinoma from an oncologic HPV perspective JO - Am J Surg Pathol VL - 41 UR - https://doi.org/10.1097/PAS.0000000000000929 DO - 10.1097/PAS.0000000000000929 ID - Gelwan2017 ER - TY - JOUR AU - Perry, M. E. PY - 1994 DA - 1994// TI - The specialised structure of crypt epithelium in the human palatine tonsil and its functional significance JO - J Anat VL - 185 ID - Perry1994 ER - TY - JOUR AU - Marur, S. AU - D’Souza, G. AU - Westra, W. H. AU - Forastiere, A. A. PY - 2010 DA - 2010// TI - HPV-associated head and neck Cancer: a virus-related Cancer epidemic – A Review of Epidemiology, Biology, Virus Detection and Issues in Management JO - Lancet Oncol VL - 11 UR - https://doi.org/10.1016/S1470-2045(10)70017-6 DO - 10.1016/S1470-2045(10)70017-6 ID - Marur2010 ER - TY - JOUR AU - Henderson, S. AU - Chakravarthy, A. AU - Su, X. AU - Boshoff, C. AU - Fenton, T. R. PY - 2014 DA - 2014// TI - APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development JO - Cell Rep VL - 7 UR - https://doi.org/10.1016/j.celrep.2014.05.012 DO - 10.1016/j.celrep.2014.05.012 ID - Henderson2014 ER - TY - JOUR PY - 2017 DA - 2017// TI - Integrated genomic and molecular characterization of cervical cancer JO - Nature VL - 543 UR - https://doi.org/10.1038/nature21386 DO - 10.1038/nature21386 ID - ref84 ER - TY - JOUR AU - Bancroft, C. C. AU - Chen, Z. AU - Yeh, J. AU - Sunwoo, J. B. AU - Yeh, N. T. AU - Jackson, S. PY - 2002 DA - 2002// TI - Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-κB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines JO - Int J Cancer VL - 99 UR - https://doi.org/10.1002/ijc.10398 DO - 10.1002/ijc.10398 ID - Bancroft2002 ER - TY - JOUR AU - Lui, V. W. Y. AU - Hedberg, M. L. AU - Li, H. AU - Vangara, B. S. AU - Pendleton, K. AU - Zeng, Y. PY - 2013 DA - 2013// TI - Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers JO - Cancer Discov VL - 3 UR - https://doi.org/10.1158/2159-8290.CD-13-0103 DO - 10.1158/2159-8290.CD-13-0103 ID - Lui2013 ER - TY - STD TI - Zhang J, Chen T, Yang X, Cheng H, Späth SS, Clavijo PE, et al. Attenuated TRAF3 fosters alternative activation of NF-κB and reduced expression of anti-viral interferon, TP53, and RB to promote HPV-positive head and neck cancers. Cancer Res. 2018;78(16):4613–4626. https://doi.org/10.1158/0008-5472.CAN-17-0642. ID - ref87 ER - TY - JOUR AU - Nave, H. AU - Gebert, A. AU - Pabst, R. PY - 2001 DA - 2001// TI - Morphology and immunology of the human palatine tonsil JO - Anat Embryol (Berl) VL - 204 UR - https://doi.org/10.1007/s004290100210 DO - 10.1007/s004290100210 ID - Nave2001 ER - TY - JOUR AU - Young, L. S. AU - Dawson, C. W. PY - 2014 DA - 2014// TI - Epstein-Barr virus and nasopharyngeal carcinoma JO - Chin J Cancer VL - 33 UR - https://doi.org/10.5732/cjc.014.10197 DO - 10.5732/cjc.014.10197 ID - Young2014 ER - TY - JOUR AU - Chung, G. T. -. Y. AU - Lou, W. P. -. K. AU - Chow, C. AU - Choy, K. -. W. AU - Leung, A. W. -. C. PY - 2013 DA - 2013// TI - Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma JO - J Pathol VL - 231 UR - https://doi.org/10.1002/path.4239 DO - 10.1002/path.4239 ID - Chung2013 ER -