| |
Oral Cavity HPV-associated
|
Oral Cavity HPV -
|
|---|
|
HR (95% CI)
|
P
|
HR (95% CI)
|
P
|
|---|
|
Mean age
|
1.02 (1.00–1.04)
|
0.010
|
1.02 (1.02–1.02)
|
< 0.001
|
|
Ethnicity
|
|
White
|
1.00
| |
1.00
| |
|
Black
|
1.88 (1.14–3.11)
|
0.013
|
0.93 (0.79–1.09)
|
0.41
|
|
American Indian/Eskimo
|
a
| |
1.18 (0.52–2.64)
|
0.68
|
|
Asian/Pacific Islander
|
1.60 (0.64–4.00)
|
0.312
|
0.93 (0.71–1.22)
|
0.63
|
|
Other
|
0.65 (0.09–4.78)
|
0.678
|
0.54 (0.30–0.99)
|
0.05
|
|
Sex
|
|
Men
|
1.00
| |
1.00
| |
|
Women
|
0.71 (0.50–0.99)
|
0.048
|
0.87 (0.78–0.95)
|
0.004
|
|
AJCC Clinical Staging
|
|
T Staging
| | | | |
|
T0
|
1.00
| |
1.00
| |
|
T1
|
0.36 (0.07–1.65)
|
0.189
|
0.45 (0.14–1.43)
|
0.18
|
|
T2
|
0.61 (0.13–2.80)
|
0.529
|
0.79 (0.25–2.49)
|
0.70
|
|
T3
|
0.90 (0.19–4.21)
|
0.903
|
1.07 (0.34–3.38)
|
0.90
|
|
T4
|
1.33 (0.29–5.98)
|
0.707
|
1.19 (0.37–3.73)
|
0.76
|
|
TX
|
0.67 (0.11–4.00)
|
0.666
|
1.36 (0.39–4.70)
|
0.63
|
|
N Staging
| | | | |
|
N0
|
1.00
| |
1.00
| |
|
N1
|
1.07 (0.70–1.63)
|
0.743
|
1.54 (1.34–1.77)
|
< 0.001
|
|
N2
|
1.08 (0.75–1.55)
|
0.651
|
1.72 (1.52–1.94)
|
< 0.001
|
|
N3
|
0.88 (0.26–2.93)
|
0.836
|
2.12 (1.49–3.03)
|
< 0.001
|
|
NX
|
1.30 (0.17–9.88)
|
0.795
|
1.19 (0.75–1.89)
|
0.45
|
|
Insurance Status
|
|
Not Insured
|
1.00
| |
1.00
| |
|
Private Insurance/Managed Care
|
0.74 (0.42–1.32)
|
0.319
|
0.81 (0.65–1.00)
|
0.06
|
|
Medicaid
|
1.82 (0.96–3.43)
|
0.064
|
1.27 (1.00–1.60)
|
0.043
|
|
Medicare
|
1.32 (0.72–2.41)
|
0.355
|
1.04 (0.83–1.30)
|
0.72
|
|
Other Government
|
0.83 (0.31–2.19)
|
0.713
|
1.17 (0.78–1.76)
|
0.44
|
|
Median Income Quartiles 2008–2012
|
|
< $38,000
|
1.00
| |
1.00
| |
|
$38,000–$47,999
|
1.38 (0.88–2.17)
|
0.160
|
0.84 (0.73–0.96)
|
0.02
|
|
$48,000–$62,999
|
1.49 (0.96–2.33)
|
0.075
|
0.90 (0.79–1.03)
|
0.14
|
|
$63,000 +
|
1.37 (0.87–2.16)
|
0.169
|
0.77 (0.67–0.88)
|
< 0.001
|
|
Treatment Group
|
|
No treatment
|
1.00
| |
1.00
| |
|
Radiation only
|
0.56 (0.25–1.23)
|
0.151
|
0.49 (0.37–0.63)
|
< 0.001
|
|
Radiation and Chemo
|
0.42 (0.22–0.82)
|
0.011
|
0.44 (0.35–0.55)
|
< 0.001
|
|
Surgery and Radiation
|
0.23 (0.10–0.50)
|
< 0.001
|
0.33 (0.26–0.43)
|
< 0.001
|
|
Surgery, Chemotherapy and Radiation
|
0.59 (0.30–1.15)
|
0.127
|
0.42 (0.33–0.53)
|
< 0.001
|
|
Surgery only
|
0.48 (0.24–0.94)
|
0.033
|
0.37 (0.29–0.45)
|
< 0.001
|
|
Chemotherapy Only
|
1.18 (0.49–2.82)
|
0.710
|
0.84 (0.61–1.16)
|
0.31
|
- aInsufficient sample size
