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High suspicion
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Solid hypoechoic nodule or solid hypoechoic component of a partially cystic nodule with one or more of the following features: irregular margins (infiltrative, microlobulated), microcalcifications, taller than wide shape, rim calcifications with small extrusive soft tissue component, evidence of ETE
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>70–90
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Recommend FNA at ≥1 cm
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Intermediate suspicion
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Hypoechoic solid nodule with smooth margins without microcalcifications, ETE, or taller than wide shape
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10–20
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Recommend FNA at ≥1 cm
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Low suspicion
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Isoechoic or hyperechoic solid nodule, or partially cystic nodule with eccentric solid areas, without microcalcification, irregular margin or ETE, or taller than wide shape.
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5–10
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Recommend FNA at ≥1.5 cm
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Very low suspicion
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Spongiform or partially cystic nodules without any of the sonographic features described in low, intermediate, or high suspicion patterns.
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<3
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Consider FNA at ≥2 cm Observation without FNA is also a reasonable option
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Benign
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Purely cystic nodules (no solid component)
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<1
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No biopsy
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