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Table 3 Summary of head and neck cancer clinical samples in genome sequencing studies

From: Genomically personalized therapy in head and neck cancer

Study

Total samples

Oral cavity

Oropharynx

Hypopharynx

Larynx

Other primary sites

Lymph nodes

Metastatic samples

HPV-Positive

HPV-Negative

Stransky et al. [9]

92

51 (55 %)

15 (16 %)

7 (8 %)

15 (16 %)

2 (2 %)

-

-

13 (14 %)

79 (86 %)

Agrawal et al. [10]

32

NK

NK

NK

NK

NK

-

-

4 (12 %)

28 (88 %)

Chung et al. [11]

252

53 (21 %)

12 (5 %)

-

7 (3 %)

103 (41 %)

25 (10 %)

80 (32 %)

84 (33 %)

168 (67 %)

Seiwert et al. [12]

120

23 (19 %)

67 (56 %)

8 (7 %)

19 (16 %)

3 (2 %)

-

-

51 (42 %)

69 (58 %)

Pickering et al. [13]

38

38 (100 %)

-

-

-

-

-

-

NK

NK

TCGA [14]

279

172 (62 %)

33 (12 %)

-

72 (26 %)

-

-

-

36 (13 %)

243 (87 %)

  1. Abbreviation: NK not known, TCGA The Cancer Genome Atlas