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Table 3 Summary of head and neck cancer clinical samples in genome sequencing studies

From: Genomically personalized therapy in head and neck cancer

Study Total samples Oral cavity Oropharynx Hypopharynx Larynx Other primary sites Lymph nodes Metastatic samples HPV-Positive HPV-Negative
Stransky et al. [9] 92 51 (55 %) 15 (16 %) 7 (8 %) 15 (16 %) 2 (2 %) - - 13 (14 %) 79 (86 %)
Agrawal et al. [10] 32 NK NK NK NK NK - - 4 (12 %) 28 (88 %)
Chung et al. [11] 252 53 (21 %) 12 (5 %) - 7 (3 %) 103 (41 %) 25 (10 %) 80 (32 %) 84 (33 %) 168 (67 %)
Seiwert et al. [12] 120 23 (19 %) 67 (56 %) 8 (7 %) 19 (16 %) 3 (2 %) - - 51 (42 %) 69 (58 %)
Pickering et al. [13] 38 38 (100 %) - - - - - - NK NK
TCGA [14] 279 172 (62 %) 33 (12 %) - 72 (26 %) - - - 36 (13 %) 243 (87 %)
  1. Abbreviation: NK not known, TCGA The Cancer Genome Atlas