Fig. 2From: Optimal use of lenvatinib in the treatment of advanced thyroid cancerManagement of palmar–plantar erythrodysesthesia. Physicians should instruct patients to care for the skin on their hands and feet at the initiation of lenvatinib. The concomitant use of a moisturizing cream and steroid ointments, and a change in the schedule of lenvatinib treatment should be considered according to the severity of palmar–plantar erythrodysesthesia. *Steroid ointments of Group 2 (very strong: e.g., difluprednate) or Group 3 (strong: e.g., betamethasone valerate) are recommended. The treatment regimen and schedule should be determined by a dermatologistBack to article page